There are many different weapons used within the series of Trigun. Some which are very powerful and some which are non lethal physically, but can be used against enemies to deter them from fighting against Vash. Below you can find out information from the weapons used throughout the series of Trigun.
The Crucifix: This is a weapon used in Trigun, which is a very large weapon and is also very heavy. This weapon however is made up of more than one weapon in total. Think of it as a large cross, the large bottom part contains a machinegun. The top contains a rocket launcher type weapon, one side contains quite a few hand guns, and on the otherside is ammunition for the machinegun
Custom Revolver AGL Arms .45 Long Colt: This weapon is based on a normal revolover but has custom features. This weapon belongs to Vash and is his preferred weapon of choice. It is an extremely accurate and powerful weapon, as Vash prefers this weapon because of his sharp shooting and extreme accuracy.
Derringers: This is a very small weapon, which uses which is most likely 9mm or .45 auto rounds to fire. It belongs to Meryl Strife, she holds up to 40 of these small weapons under her cape for use when she needs them.
Stun Gun: Owned my Milly Thompson this weapon is quite a large weapon in size. The stun gun is made up of 6-8 barrels which fire large tubes which fold out when fired. They are used to knock down opponents and neutrolize them so that they are incapable to move.
Toy Guns: These are not real weapons as they are just toys that kids use to play gun fights with. Vash also uses them to make a fool out of bad guys. He keeps this to demonstrate to bad guys how easily he can shoot them if he wanted to.
Pump Action Shotguns: This is a weapon which goons use against Vash when they try to fight him. These weapons are not used very often but are used by goons within the series